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Frank Wuytack Selected Research

Benign Familial Pemphigus (Hailey Hailey Disease)

1/2017Structure/activity relationship of thapsigargin inhibition on the purified Golgi/secretory pathway Ca2+/Mn2+-transport ATPase (SPCA1a).
2/2006Dissection of the functional differences between human secretory pathway Ca2+/Mn2+-ATPase (SPCA) 1 and 2 isoenzymes by steady-state and transient kinetic analyses.
11/2005Functional comparison between secretory pathway Ca2+/Mn2+-ATPase (SPCA) 1 and sarcoplasmic reticulum Ca2+-ATPase (SERCA) 1 isoforms by steady-state and transient kinetic analyses.
7/2003Effect of Hailey-Hailey Disease mutations on the function of a new variant of human secretory pathway Ca2+/Mn2+-ATPase (hSPCA1).

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Frank Wuytack Research Topics

Disease

5Heart Failure
08/2006 - 06/2003
4Benign Familial Pemphigus (Hailey Hailey Disease)
01/2017 - 07/2003
3Breast Neoplasms (Breast Cancer)
10/2019 - 01/2017
3Prostatic Neoplasms (Prostate Cancer)
01/2017 - 03/2002
2Hypertrophy
06/2012 - 12/2003
1Skin Diseases (Skin Disease)
10/2019
1Kufor-Rakeb syndrome
07/2015
1Parkinson Disease (Parkinson's Disease)
07/2015
1Neointima
03/2012
1Colonic Neoplasms (Colon Cancer)
08/2010
1Weight Loss (Weight Reduction)
12/2009
1Hypertension (High Blood Pressure)
12/2009
1Obesity
12/2009
1Atherosclerosis
12/2009
1Ataxia (Dyssynergia)
11/2008
1Atrophy
11/2008
1Muscular Atrophy (Muscle Atrophy)
11/2008
1Necrosis
11/2004
1Neoplasms (Cancer)
11/2004
1Blister (Bulla)
07/2003
1Dilated Cardiomyopathy (Cardiomyopathy, Congestive)
06/2003

Drug/Important Bio-Agent (IBA)

9Adenosine Triphosphatases (ATPase)IBA
10/2019 - 07/2003
3phospholambanIBA
06/2012 - 09/2004
3Protein Isoforms (Isoforms)IBA
11/2008 - 12/2003
2Adrenergic Agents (Adrenergic Drugs)IBA
12/2009 - 08/2006
2Proteins (Proteins, Gene)FDA Link
06/2003 - 03/2002
1Phenobarbital (Luminal)FDA Link
04/2017
1SynucleinsIBA
07/2015
1LipidsIBA
07/2015
1CalcineurinIBA
06/2012
1DesminIBA
03/2012
1CholesterolIBA
08/2010
1CollagenIBA
12/2009
1Carvedilol (Coreg)FDA LinkGeneric
03/2005
1AntioxidantsIBA
03/2005
1Adrenergic Receptors (Adrenergic Receptor)IBA
03/2005
1Insulin (Novolin)FDA Link
11/2004
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
11/2004
1CalciumIBA
11/2004
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
11/2004
1Sarcoplasmic Reticulum Calcium-Transporting ATPasesIBA
09/2004
1CalreticulinIBA
03/2002

Therapy/Procedure

1Therapeutics
01/2017
1Denervation
11/2008